Prospects of application of the complex with artichoke and garlic in clinical medicine


  • Ye. F. Grintsov National University of Pharmacy, Ukraine
  • A. I. Fedosov National University of Pharmacy, Ukraine
  • V. A. Moroz National University of Pharmacy, Ukraine
  • Yu. V. Timchenko National University of Pharmacy, Ukraine
  • A. S. Shalamay PJSC SIC “Borshchahivskiy CPP”, Ukraine



artichoke extract, garlic, antioxidants, herbal medicines


Today herbal medicines become more and more popular in the world due to their inherent advantages over drugs of the chemical origin. A long historical experience of application, the high safety profile, its complex action, as well as the possibility of the long-term use without significant side effects cause an increase in their consumption around the world. At the same time, the practice of using herbal medicines is significantly hindered by the lack of scientific information about their mechanisms of action, potential adverse reactions, contraindications and interactions with other drugs and food. The publication considers scientometric data on the possible use of medicines based on leaves of artichoke and garlic in the clinical medicine. The existing information based on the preclinical and clinical studies has been analyzed. Particular attention is paid to the results of controlled clinical trials. The attention is drawn to very good tolerability and safety of herbal medicines from artichoke and garlic, which, in particular, allows their use in children, geriatric patients, pregnancy, etc. The conclusion has been made that these medicines have significant prospects for widespread use, and the existing scientific data allow their wide clinical use separately and in combination with a variety of diseases and pathological conditions.

Author Biographies

Ye. F. Grintsov, National University of Pharmacy

Candidate of Medicine (PhD), associate professor, chief physician of the Clinical Diagnostic Center

A. I. Fedosov, National University of Pharmacy

Candidate of Pharmacy (PhD), associate professor of the Medicinal Chemistry Department

V. A. Moroz, National University of Pharmacy

Doctor of Medicine (Dr. habil.), professor of the Department of Clinical Pharmacology and Clinical Pharmacy

Yu. V. Timchenko, National University of Pharmacy

Candidate of Medicine (PhD), teaching assistant of the Department of Clinical Pharmacology and Clinical Pharmacy

A. S. Shalamay, PJSC SIC “Borshchahivskiy CPP”

Candidate of Chemistry (PhD), director in science


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Clinical Pharmacology and Pharmacotherapy