Prospects of application of the complex with artichoke and garlic in clinical medicine

Ye. F. Grintsov, A. I. Fedosov, V. A. Moroz, Yu. V. Timchenko, A. S. Shalamay

Abstract


Today herbal medicines become more and more popular in the world due to their inherent advantages over drugs of the chemical origin. A long historical experience of application, the high safety profile, its complex action, as well as the possibility of the long-term use without significant side effects cause an increase in their consumption around the world. At the same time, the practice of using herbal medicines is significantly hindered by the lack of scientific information about their mechanisms of action, potential adverse reactions, contraindications and interactions with other drugs and food. The publication considers scientometric data on the possible use of medicines based on leaves of artichoke and garlic in the clinical medicine. The existing information based on the preclinical and clinical studies has been analyzed. Particular attention is paid to the results of controlled clinical trials. The attention is drawn to very good tolerability and safety of herbal medicines from artichoke and garlic, which, in particular, allows their use in children, geriatric patients, pregnancy, etc. The conclusion has been made that these medicines have significant prospects for widespread use, and the existing scientific data allow their wide clinical use separately and in combination with a variety of diseases and pathological conditions.


Keywords


artichoke extract; garlic; antioxidants; herbal medicines

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DOI: https://doi.org/10.24959/cphj.17.1431

Abbreviated key title: Klìn. farm.

ISSN 2518-1572 (Online), ISSN 1562-725X (Print)