Quantitative determination of biologically active substances with the antimicrobial action in gastric teas

A. I. Fedosov, V. S. Kyslychenko, O. A. Kyslychenko


Herbal teas with the astringent, anti-inflammatory, antihemorragic, reparative and antimicrobial activity are often used for treatment of gastric diseases. Two teas have been suggested – gastric tea and gastric tea No.3. Gastric tea consists of chamomile flowers, yarrow herb, calendula flowers, St. John’s wort herb and peppermint leaves. Gastric tea No.3 contains buckthorn bark, nettle leaves, peppermint leaves, valeriana rhizomes with roots and sweetflag rhizomes. Gastric herbal teas can be used for a long time for treating chronic gastro-intestinal system diseases and as a complex treatment of acute pathology. Biologically active compounds of these teas contain essential oils, tannins, flavonoids, hydroxycinnamic acids, compounds of the terpenoid origin and mineral elements. The results of quantitative determination of essential oil and the amount of polyphenolic compounds in gastric tea and gastric tea No.3 are given; these specific classes of compounds exactly show the antimicrobial activity. The quantitative content of essential oil was determined with the help of hydrodistillation, and the content of the amount of polyphenolic compounds – by spectrophotometry. According to the results obtained the essential oil content in gastric tea was 0.85%, in gastric tea No.3 – 0.98%. The polyphenolic compounds content in gastric tea was 7.46%, in gastric tea No.3 – 8.34%. This particular content of the biologically active substances determines the antimicrobial activity of gastric teas. The data obtained shows the prospects for further research of the biologically active substances of gastric teas revealing the antimicrobial activity.


herbal teas; antimicrobial activity; gastric diseases; biologically active substances; essential oil; polyphenolic compounds


Бурда Н.Є., Журавель І.О., Кисличенко В.С. та ін. // Укр. мед. альманах. – 2010. – Т. 13, №5. – С. 51-53.

Волошина А.А., Кисличенко В.С., Журавель І.О., Бурда Н.Є. // Укр. журн. клін. та лабораторної медицини. – 2012. – Т. 7, №4. – С. 202-203.

Державна фармакопея України / Державне підприємство «Науково-експертний фармакопейний центр». – 1-е вид. – Х.: РІРЕГ, 2001. – Доп. 1. – 2004. – 520 с.

Системная фитотерапия: Учебное пособие / Под ред. В.С.Кисличенко, А.В.Зайченко, И.А.Журавель. – Х.: Изд-во НФаУ; «Золотые страницы», 2008. – 256 с.

Ahmet Alim, Ismihan Goze, Ali Cetin et al. // African J. of Microbiol. Res. – 2009. – Vol. 3 (8). – P. 422-425.

Alves M.J., Ferreira I.C., Froufe H.J. et al. // J. Appl. Microbiol. – 2013. – Vol. 115 (2). – P. 346-357.

Antonio Carraturo, Katia Raieta, Idolo Tedesco // British Microbiol. Res. J. – 2014. – Vol. 4 (1). – P. 18-27.

Christina E. Maddox, Lisa M. Laur, Li Tian // Current Microbiol. – 2010. – Vol. 60 (1). – Р. 53-58.

Julien Sfeir, Corinne Lefrançois, Dominique Baudoux et al. // Evidence-Based Complementary and Alternative Medicine. – 2013. – Vol. 2013. – P. 1-9.

Leon W. Nitiema, Aly Savadogo, Jacques Simpore et al. // Intern. J. of Microbiol. Res. – 2012. – Vol. 3 (3). – Р. 183-187.

Manoj G.S., Murugan K. // Ind. J. of Natural Products and Resources. – 2012. – Vol. 3 (2). – Р. 173-183.

Marina Soković, Jasmina Glamočlija, Petar D. Marin et al. // Molecules. – 2010. – Vol. 15. – Р. 7532-7546.

Sarabjot Kaur, Poonam Mondal // J. Microbiol. Exp. – 2014. – Vol. 1 (1). – P. 1-6.

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DOI: https://doi.org/10.24959/cphj.14.1328

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Abbreviated key title: Klìn. farm.

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