Statins: pharmacoeconomic aspects of the use of hmg-coa reductase inhibitors

Authors

DOI:

https://doi.org/10.24959/cphj.19.1476

Keywords:

HMG-CoA reductase inhibitors, medicines, pharmaceutical market, affordability

Abstract

Big hopes for reducing high mortality from cardiovascular diseases are placed on statins, the use of which is due to the effective action of the drugs, broad indications,  a prolonged and positive experience of use, and a high evidence base.

Purpose. The aim of the work was the formation of a modern understanding of the market structure and analysis of the availability of HMG-CoA reductase inhibitors.

Materials and methods. The studies were conducted in accordance with the State Register of Medicinal Products of Ukraine, ATC-classification, Equalizer system data. The study was performed by statistical, logical and graphical methods, as well as methods of marketing analysis.

Results. The paper analyzes the range, cost of daily doses of drugs, physical and economic accessibility of HMG-CoA reductase inhibitors. It was determined that the market is import-dependent - the share of domestic drugs is about 35%. The drugs are structured according to the ABC classification, the leading drugs are defined. The economic and physical accessibility of the HMG-CoA reductase inhibitors, which generally indicates their high and medium availability in the pharmaceutical market of Ukraine, was analyzed.

Conclusions: Among the leaders − 9 medicines, only 2 of them - drugs of domestic production, which indicates the possibility of developing a program for the import substitution of this particular group of drugs. Depending on the INN and the manufacturer, the prices of drugs vary within very wide limits, which makes it possible to choose a drug based on its affordability.

Author Biographies

O. M. Ievtushenko, National University of Pharmacy

Doctor of Pharmaceutical Sciences, Professor, Department of  Pharmaceutical Marketing and Management

V. D. Nemtsova, National Medical University Kharkiv

PhD of Medical Science, Associate Professor, Department of Clinical Pharmacology and Internal diseases

V. V. Tchaikovsky, State Institution “Institute of Gerontology by D.F. Chebotaryov of the NAMS of Ukraine

Doctor of Medicine, Professor of the Department of Palliative and Hospice Medicine NMAPE named after P.L.Shupik, Member of the expert council on palliative medicine and geriatrics of the Ministry of Health of Ukraine

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Published

2019-03-04

Issue

Vol. 23 No. 1 (2019)

Section

Pharmacoeconomics

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