Analysis of the consumption of H2-receptor antagonists in Ukraine and European countries
DOI:
https://doi.org/10.24959/cphj.18.1462Keywords:
H2-receptor antagonists, assortment of drugs, pharmaceutical market, ATC / DDD methodology, consumption of drugsAbstract
H2-receptor antagonists are one of the main antisecretory drugs and have certain advantages in the treatment of the acid related diseases.
Aim. To assess the consumption of H2-receptor antagonists in Ukraine and European countries in 2015-2017.
Materials and methods. Data from the “Pharmexplorer” information system by Morion company were used to analyze the assortment and the consumption volumes of H2-receptor antagonists in Ukraine. The assessment of the volume, structure and dynamics of the drug consumption of this group in Ukraine was conducted based on the number of the defined daily doses (DDD) of drugs consumed using the ATC / DDD methodology, as well as by the number of the drug packs sold. The level of the drug consumption of H2-receptor antagonists by the indicator “DDDs/1000 inhabitants/day” in the countries of Europe was determined by the statistical data of these countries.
Results. In 2015-2017, H2-receptor antagonists were presented in Ukraine in the number of 2 international non-patented names, 26-29 trade names (TN), and they had rather wide range of prices pre a pack. The tendency to decrease in the number of their TN was observed from 2015 to 2017. The consumption of H2-receptor antagonists by the number of the packs sold and the number of DDDs consumed increased in Ukraine over the period under study. Ranitidine took leading positions by these indicators of consumption. Ukraine was ranked second among the European countries (Norway, Lithuania, Latvia, Estonia) by the level of consumption of H2-receptor antagonists by the indicator “DDDs/1000 inhabitants/day”. Ranitidine was the leader in consumption in all countries studied.
Conclusions. The consumption volume of H2-receptor antagonists by the number of the packs sold and the number of DDDs consumed increased in Ukraine in 2015-2017. The level of the drug consumption of this group by the indicator “DDDs / 1000 inhabitants / day” in Ukraine in 2015-2017 did not correspond to the level of consumption of H2-receptor antagonists in European countries.
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