Modern aspects of treatment of allergic dermatitis with the secondary fungal infections

Authors

  • T. G. Yarnykh National University of Pharmacy, Ukraine
  • V. S. Levchenko National University of Pharmacy, Ukraine
  • O. A. Rukhmakova National University of Pharmacy, Ukraine

DOI:

https://doi.org/10.24959/cphj.17.1421

Keywords:

allergic dermatitis, fungal infection, skin, treatment

Abstract

Allergic skin disease pathology is widespread in the world and in the last decade has attracted the attention of doctors. In Ukraine, 40 % of adults and children suffer from all types of allergic dermatitis.

The aim of this work is to study the current state of treatment of allergic dermatitis complicated with the secondary fungal infection, and substantiate the necessity for creating the extemporaneous ointment for the treatment of this skin pathology.

The known recommendations of doctors concerning the treatment of allergic dermatitis include measures aimed at excluding or reducing a contact with a variety of triggers, skin care (permanent cleaning and moisturizing) and the treatment of pruritus and chronic inflammation with anti-inflammatory medicines depending on the severity, localization of lesions of the skin, as well as skin infections associated with allergic dermatitis. In addition to the systemic therapy, the topical treatment of affected areas of the skin is also recommended for patients with allergic dermatitis. The external therapy should be carried out taking into account the clinical form and stages of the disease.

To analyze the existing extemporaneous formulations for the treatment of allergic dermatitis complicated with the secondary fungal infection prescriptions of various soft medicinal forms for treating allergic dermatitis approved by the Ministry of Public Health of Ukraine have been studied. The absence of antifungal components in their composition has been shown. The necessity of creating a new extemporaneous ointment for the treatment of allergic dermatitis complicated with the secondary fungal infection with the complex anti-allergic and antifungal action using a dry extract of licorice root, essential oil of lavender and terbinafine hydrochloride has been substantiated.

Author Biographies

T. G. Yarnykh, National University of Pharmacy

Doctor of Pharmacy (Dr. habil.), professor, head of the Drug Technology Department

V. S. Levchenko, National University of Pharmacy

5-year student of the Medical and Pharmaceutical Faculty of specialty “Clinical Pharmacy”

O. A. Rukhmakova, National University of Pharmacy

Doctor of Pharmacy (Dr. habil.), associate professor of the Drug Technology Department

References

Buddenkotte, J., Steinhoff, M. (2010). Pathophysiology and therapy of pruritus in allergic and atopic diseases. Allergy, 65 (7), 805–821. doi: 10.1111/j.1398–9995.2010.01995.x

Kotrekhova, L. P., Vasileva, N. V., Raznatovskii, K. I., Piotrovskaia, I. V. (2011). Klinicheskaia dermatologiia i venerologiia, 4, 71–75.

Sokolovskii, E. V., Monakhov, K. N., Dombrovskaia, D. K. (2011). Vestnik dermatologii i venerologii, 3, 3–6.

Kotrehova, L. P. (2010). Consilium medicum. Dermatologiia, 4, 6–11.

Kaliuzhnaia, L. D. (2010). Klinicheskaia immunologiia. Allergologiia. Infektologiia, 1, 15–19.

Bolotnaia, L. A. (2010). Ukrainskii zhurnal dermatologov, venerologov, kosmetologov, 3 (38), 47–52.

Belousova, T. A., Goriachkina, M. V., Griazeva, T. M. (2011). Consilium Medicum. Dermatologiia, 2, 18–22.

Tihonov, O. I., Yarnyh, T. H., Hritsenko, I. S., Khohlenkova, N. V. et al. (2016). Ekstemporalna retseptura (tehnolohiia, analiz, zastosuvannia). Kyiv: Ahentstvo Medychnoho Marketynhu, 352.

Downloads

Published

2017-06-14

Issue

Vol. 21 No. 2 (2017)

Section

Clinical Pharmacology and Pharmacotherapy

License

Copyright (c) 2017 National University of Pharmacy

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).