Differences of the antiplatelet treatment with acetylsalicylic acid
DOI:
https://doi.org/10.24959/cphj.16.1405Keywords:
antiplatelet therapy, acetylsalicylic acid, aspirin resistance, ischemic heart diseaseAbstract
According to the statistical forecasting the cardiovascular mortality will be 25 million cases per year in 2020. Therefore, the search for effective ways to treat and prevent cardiovascular diseases is the primary objective of the current medicine. It has been shown that one of the main groups of drugs that positively affect the duration and quality of life, are antiplatelet agents. Acetylsalicylic acid is an antiplatelet agent that is most widely used for both the primary and secondary prevention of cardiovascular diseases. This article discusses the problems of aspirin resistance, possible ways to improve the efficacy and safety of acetylsalicylic acid therapy, the impact of gender on its effectiveness, and others. There is the need for further development of methods for determining the mechanisms of formation of sensitivity and the rational prescription and correction of the therapy with acetylsalicylic acid.
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