Cost evaluation of the antihelicobacter therapy of gastroduodenal ulcers

Authors

  • O. O. Gerasymova National University of Pharmacy, Ukraine
  • A. A. Krasiuk National University of Pharmacy, Ukraine

DOI:

https://doi.org/10.24959/cphj.16.1387

Keywords:

peptic ulcer, duodenal ulcer, antihelicobacter therapy, cost of treatment

Abstract

The results of cost evaluation of the antihelicobacter therapy regimen of gastroduodenal ulcers recommended by the Ukrainian unified clinical protocol of medical care to adult patients with this disease (order of the Ministry of Health of Ukraine No. 613 dated 03.09.2014), which is based on the principles of evidence-based medicine, are presented. It has been found that most medicines used in the antihelicobacter therapy regimen were presented at the pharmaceutical market ofUkrainein2014 insufficient quantities with a wide range of prices per a drug unit. The cost ranges of the antihelicobacter therapy are: the first-line therapy – from 87.50 to 3400.88 UAH (the triple therapy – from 181.44 to 3400.88 UAH; the sequential therapy – from 87.50 to 1837.65 UAH); the second-line therapy (quadrotherapy) – from 202.60 to 2059.19 UAH; the therapy of salvation – from 157.08 to 3298.93 UAH. The total costs of therapy for the patient with therapy of salvation are from 628.62 to 10596.65 UAH. The variants of the antihelicobacter therapy regimen have been proposed. They are formed from the medicines presented at the Ukrainian pharmaceutical market and the State Formulary ofUkraine, and have the lowest costs for the course of the antihelicobacter therapy of the disease. Their use is economically feasible for the Ukrainian low solvent patients with peptic and duodenal ulcers. 

References

Адаптована клінічна настанова, заснована на доказах «Пептична виразка шлунка та дванадцятипалої кишки». – Режим доступу: http://www.dec.gov.ua/mtd/reestr.html.

Державний формуляр лікарських засобів України (шостий випуск, 2014 р.). – Режим доступу: http://www.dec.gov.ua/index.php/ua/site-terms.

Лазебник Л.Б., Гусейнзаде М.Г., Ефремов Л.И. // Качественная клиническая практика. – 2008. – №2. – С. 62-70.

Лазебник Л.Б., Машарова А.А., Гусейнзаде М.Г. // Эксперим. и клиническая гастроэнтерол. – 2006. – №4. – С. 1-6.

Маев И.В., Самсонов А.А., Голубев Н.Н. и др. // Фарматека. – 2011. – №2. – С. 10-17.

Система дослідження ринку «Фармстандарт» компанії «Моріон». – Режим доступу: http:// pharmbase.com.ua/poisk/.

Уніфікований клінічний протокол первинної, вторинної (спеціалізованої) медичної допомоги «Пептична виразка шлунка та дванадцятипалої кишки у дорослих». – Режим доступу: http:// www.dec.gov.ua/mtd/reestr.html.

Фомин П.Д., Никишаев В.И. // Здоров’я України. – 2010. – №2. – С. 8-11.

Харченко Н.В., Опанасюк Н.Д., Токарь Д.В. // Сучасна гастроентерол. – 2009. – №5 (49). – С. 89-93.

Jyh-Chin Yang, Chien-Wei Lu, Chun-Jung Lin // World J. Gastroenterol. – 2014. – Vol. 20, Iss. 18. – Р. 5283-5293.

Malfertheiner P., Megraud F., O’Morain C.A. et al. // Gut . – 2012. – №61. – Р. 646-664.

Sebahat Basyigit, Ayse Kefeli, Ferdane Pirincci Sapmaz et al. // Bosn. J. Basic Med. Sci. – 2015. – Vol. 15, №4. – Р. 50-54.

Wei-Ping Bi, Hui-Bin Man, Mao-Qiang Man // World J. of Gastroenterol. – 2014. – Vol. 20, Iss. 45. – P. 17020-17028.

Zagari R.M., Romano M., Ojetti V. et al. // Digestive and Liver Disease. – 2015. – №47. – Р. 903-912.

Downloads

Published

2016-06-14

Issue

Vol. 20 No. 2 (2016)

Section

Pharmacoeconomics

License

Copyright (c) 2016 National University of Pharmacy

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).