Evaluation of pharmacotherapy of patients with hypothyroidism by the methods of frequence, ABC-, VEN-analyses

Authors

  • I. O. Fedyak SHHE «Ivano-Frankivsk National Medical University», Ukraine
  • D. V. Semenov SHHE «Ivano-Frankivsk National Medical University», Ukraine
  • A. Yu. Pustovit SHHE «Ivano-Frankivsk National Medical University», Ukraine

DOI:

https://doi.org/10.24959/cphj.14.1291

Keywords:

hypothyroidism, iodine deficiency, retrospective methods of clinical enonomic analysis, frequence, ABC-, VEN-analysis, L-thyroxine

Abstract

The article presents the results of a comprehensive clinical economic analysis of patients with the iodine deficiency syndrome and hypothyroidism. The study was conducted at the Regional Clinical Hospital of Ivano-Frankivsk. As it is evidenced by the results of frequency analysis, in total 244 prescriptions of 73 drugs – an average of five prescriptions per a medical history sheet were made for 47 patients. In most cases for the treatment of patients L-thyroxine (Berlin-Chemie AG, Germany), which 85% of patients received, was used. However, taken into account the great number of prescriptions for various drugs, L-thyroxine was prescribed only in 16.4% of cases in general. Besides the replacement therapy with L-thyroxine, patients mostly received treatment of concomitant diseases. The list of drugs, which cost was about 80% of the total cost of therapy (group A cost) was determined by the ABC-distribution method; the part of them was 18% in the total names of drugs. Group B was comprised of 31% of all medicines, which cost was 2034.19 UAH – 15% of the total cost of pharmacotherapy. The part of group C by cost was 6%, it contained the largest number of drugs – 37, which was 51%.                                                          The results of the combined ABC/VEN-analyses determined that the highest proportion of costs for the pharmacotherapy conducted fell to the drugs of group N being secondary by importance. Group E was represented by 12 drugs. And the necessary group V was represented only by three drugs (6.4%). The ABC/VEN-analyses conducted confirmed the conclusion of frequency analysis since expenditures were distributed irrationally concerning the importance of the drugs according to the clinical protocol. After the introduction of compulsory health insurance in Ukraine this state of distribution of expenses would be unacceptable.

References

Боднар П.М., Щербак О.В., Комісаренко Ю.Г. // Ендокринол. – 2002. – №2. – С. 91-101.

Воробьев П.А., Авксентьева М.В., Юрьев А.С., Сура М.В. Клинико-экономический анализ (оценка, выбор медицинских технологий и управление качеством медицинской помощи). – М.: Ньюдиамед, 2004. – 404 с.

Посилкіна О.В., Братішко Ю.С. Фармакоекономічний аналіз лікування гіпотиреозу: Матер. V наук.- практ. конф. «Фармакоекономіка в Україні: стан та перспективи розвитку». – Х.: Вид-во НФаУ, 2012 – С. 217-220.

Посилкіна О.В., Попов С.Б., Зайченко Г.В. // Клінічна фармація. – 2000. – №4. – С. 33-39.

Фармакоекономіка: Навч. посіб. для студ. ВНЗ / За ред. Л.В.Яковлєвої. – Вінниця: Нова Книга, 2009. – 208 с.

Шідловський В.О., Дейкало І.М. Йододефіцитні захворювання: діагностика, лікування, профілактика. – Тернопіль: Укрмедкнига, 2006. – 124 с.

Щербак І.О. // Укр. мед. часопис online. – 2012. – Режим доступу: http://www.umj.com.ua/article/ 33434/jododeficit-v-ukraini-formuye-vidstale-suspilstvo.

Folland S., Goodman A.C., Stano M. // Upper Saddle River, NJ. – 2010. – №2. – Р. 20-29.

Kenkel D. Workshop on Strengthening Benefit-Cost Methodology for the Evaluation of Early Childhood Interventions // Valuation in Health Economics. Presented at Valuation of Outcomes and Resources. – 2009. – №4-5. – Режим доступу: www.bocyf.org/kenkel_presentation.pdf.

Neumann P.J. // JAMA. – 2011. – Vol. 305, №17. – Р. 1803-1807.

Neumann P.J., Weinstein M.C. // NEJM. – 2010. – №363. – Р. 1495-1497.

Nord E., Pinto J.L., Richardson J. et al. // Health Economics. – 1999. – №8 (1). – Р. 25-39.

Pollack A. Medicare Will Continue to Cover 2 Expensive Cancer Drugs // The New York Times. – 2011. – №1. – Режим доступу: http://www.nytimes.com/2011/07/01/business/01drug.html.

Principles of pharmacoeconomic analysis of drug therapy. – Режим доступу: http://www.ncbi.nlm.nih.gov/pubmed/10147037.

What is iodine deficiency? – Режим доступу: http://www.localhealth.com/article/iodine-deficiency.

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Published

2014-03-03

Issue

Vol. 18 No. 1 (2014)

Section

Pharmacoeconomics

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