Section Details

Pre-clinical studies of new drugs

Issue Title
Vol 23, No 1 (2019) In vitro antimicrobial activity of a highly dispersed silica and polyhexamethylene guanidine hydrochloride (PHMG-HC) composite for local infections treatment Abstract   PDF
A. I. Doroshenko, O. B. Balko, Ye. P. Voronin, A. M. Doroshenko, G. V. Zaychenko
Vol 23, No 1 (2019) The study of the subchronic toxicity of the cream with cerium dioxide nanoparticles in cutaneous application in rabbits Abstract   PDF
G. V. Zaychenko, O. A. Pokotylo, N. S. Nikitina
Vol 23, No 1 (2019) The dynamics of the antidepressant effect of atristamine in the repeated dose study Abstract   PDF (Українська)
I. M. Podolsky
Vol 23, No 1 (2019) The study of the sedative effect of “sedosten” extract Abstract   PDF (Українська)
L. V. Galuzinska, O. S. Kukhtenko
Vol 23, No 1 (2019) The study of the antiulcer effect of the lyophilized extract of fireweed herb on the model of ethanol-prednisolone stomach damage in rats Abstract   PDF (Українська)
H. I. Feshchenko, O. M. Oleshchuk, S. M. Marchyshyn, O. Yu. Koshova
Vol 23, No 1 (2019) Dеvelopment of the analytical diagnostics of atomoxetine poisonings Abstract   PDF (Українська)
S. A. Karpushyna, S. V. Baiurka, L. Yu. Tomarovska
Vol 22, No 4 (2018) Variability of the effect of atristamine and imipramine on the depressive behavior of mice in the aspect of circadian factors Abstract   PDF (Українська)
I. M. Podolsky, S. Yu. Shtrygol’, V. V. Tsyvunin
Vol 22, No 4 (2018) Renal effects of the sulfur-containing aminoacid derivatives (ademetionine, taurin and glutathion) in conditionally healthy animals Abstract   PDF
V. M. Drachuk, I. I. Zamorskii, T. S. Shchudrova, O. M. Goroshko
Vol 22, No 4 (2018) The experimental study of the local irritating action of N-acetylglucosamine and quercetin in intramuscular administration Abstract   PDF (Українська)
S. K. Shebeko, A. S Shalamay, O. O. Liapunova
Vol 22, No 4 (2018) The evaluation of the effect of the drug “Arthritan” on the morphofunctional state of the internal organs of rats under the conditions of the chronic toxicity study Abstract   PDF (Українська)
Yu. M. Naboka, N. P. Zubitska, S. K. Shebeko, I. A. Otrishko
Vol 22, No 4 (2018) The preclinical study of a new nasal spray with the anti-inflammatory properties: the effect on the leukotriene-induced inflammation Abstract   PDF
T. S. Zhulai
Vol 22, No 4 (2018) The antiexudative action of the plant extract “Venosten” Abstract   PDF (Українська)
A. L. Zagayko, O. S. Kukhtenko, L. V. Galuzinska
Vol 22, No 3 (2018) The influence of goutweed (aegopodium podagraria l.) Extract and tincture on the behavioural reactions Of mice against the background of caffeine-sodium benzoate Abstract   PDF (Українська)
O. V. Tovchiga, S. J. Shtrygol', A. A. Balia
Vol 22, No 3 (2018) The histomorphological study of the nephroprotective properties of Gluquamine in the experimental glomerulonephritis Abstract   PDF (Українська)
S. K. Shebeko, I. A. Zupanets, V. V. Propisnova, A. S. Shalamay
Vol 22, No 3 (2018) The study of acute toxicity of drugs on the basis of the plant raw material for non-hormonal therapy of the climacteric syndrome Abstract   PDF
І. S. Konovalenko, N. P. Polovko, D. V. Litkyn, A. L. Zagayko
Vol 22, No 3 (2018) The study of the peculiarities of the diuretic action of 2-oxoindoline acylated derivative – N-[(2-oxoindoliniliden-3)-2-oxyacetyl]-valine propyl ester-[(2-oxoindoliniliden-3)-2-oxyacetyl]-valine propyl este Abstract   PDF
А. Yu. Markina, O. Ya. Mishсhenko
Vol 22, No 3 (2018) The effect of melatonin and N-acetylcysteine on the state of the orientation research activity in rats under conditions of the experimental diabetes mellitus Abstract   PDF (Українська)
O. A. Fitsner, M. V. Khaitovych, I. M. Ryzhko, L. I. Holopykho
Vol 22, No 3 (2018) The antiulcer effect of the thick water-alcohol extract from unripe walnut fruits on the model of acute alcohol-prednisolone ulcer of the rat’s stomach in different modes of administration Abstract   PDF (Українська)
Ie. V. Zalygina, O. A. Podpletnya, K. V. Sokolova
Vol 22, No 3 (2018) Research of the influence of a new gel which contains extract of oak bark and aloe extract on the mucous membrane of oral cavity under the conditions of experimental stomatitis Abstract   PDF
N. A. Tsubanova, D. S. Zhurenko, T. S. Sakharova
Vol 22, No 2 (2018) The study of the analeptic activity of derivatives of sulfur- and nitrogen-containing heterocycles on the model of thiopental narcosis Abstract   PDF
I. V. Kabachna, S. M. Drogovoz, V. I. Kabachnyy, Yu. Yu. Serdiukova
Vol 22, No 2 (2018) The experimental study of the effect of Gluquamine on the electrolyte metabolism in rats with renal failure Abstract   PDF (Українська)
S. K. Shebeko, I. A. Zupanets, A. S. Shalamay
Vol 22, No 1 (2018) Dynamics of the cytokine blood profile under the effect of wound healing medicinal products with different mechanisms of action in the experiment Abstract   PDF
T. I. Iermolenko, O. V. Kryvoshapka, O. I. Pautina
Vol 22, No 1 (2018) The experimental study of antioxidant properties of Gluquamine under the conditions of diabetic nephropathy development Abstract   PDF (Українська)
S. K. Shebeko, I. A. Zupanets, A. S. Shalamay
Vol 22, No 1 (2018) The effects of goutweed (Aegopodium podagraria L.) tincture on the background of toxic doses of allopurinol with the excessive intake of purine derivatives and proteins Abstract   PDF (Українська)
O. V. Tovchiga
Vol 21, No 4 (2017) The standardized model of alcoholic anesthesia for the purposeful screening of analeptics Abstract   PDF
I. V. Kabachna, S. M. Drogovoz, V. I. Kabachnyy, Yu. Yu. Serdiukova
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