The significance of selecting phytopreparations for individualized therapy of acute rhinosinusitis
DOI:
https://doi.org/10.24959/cphj.17.1444Keywords:
acute rhinosinusitis, Sinupret®, rational pharmacotherapy, pharmaceutical careAbstract
The article is devoted to modern approaches to the treatment of acute rhinosinusitis taking into account the basic principles of the rational pharmacotherapy. Today acute rhinosinusitis (ARS) remains in the leading position among other diseases in outpatient practice, therefore, the choice of the optimal treatment tactics and the optimal drug in each clinical case is of particular importance. The drugs of choice for acute uncomplicated rhinosinusitis are herbal preparations. The phytopreparations have an effect on all links of the pathogenesis of the disease due to the complex action of their biologically active substances. The phytopreparation Sinupret® (Bionorica CE, Germany) is very often recommended by doctors and pharmacists for treating rhinitis, sinusitis and their complications. Priority of the choice of the drug is determined by its high efficiency and safety proven by numerous preclinical and clinical studies, the long experience of use and the presence of several dosage forms. Despite the common name each of the drugs of this brand has its own characteristics. They differ in the specificity of the dosage form, the physicochemical state of the active pharmaceutical substance, the dose of the active substances. Various Sinupret® modifications are important for the individualized rational pharmacotherapy of patients with ARS provided by both a physician and a pharmacist. When providing pharmaceutical care a pharmacist select over-the-counter medicines taking into account their effectiveness, safety, quality and economic expediency.
References
Krivopalov, A. A. (2016). Meditcinskii sovet, 6, 22–25.
Koch, A. K., Klose, P., Lauche, R. et. al. (2016). Systematic Review of Phytotherapy for Acute Rhinosinusitis. Forsch Komplementmed, 23 (3), 165–169. doi: 10.1159/000447467
Dіkhtiaruk, O. V. (2015). Ukrainskyi naukovo–medychnyi molodіzhnyi zhurnal, 2 (88), 31–35.
Riazantcev, S. V., Krivopalov, A. A., Shamkina, P. A. (2017). Meditcinskii sovet, 16, 78–83.
Passali, D., Cambi, J., Passali, F. M., Bellussi, L. M. (2015). Phytoneering: a new way of therapy for rhinosinusitis. Acta Otorhinolaryngol Ital, 35 (1), 1–8.
Lopatin, A. S., Varvianskaia, A. V. (2014). Meditcinskii sovet, 3, 24–26.
Kirsanov, D. (2017). Ezhenedelnik Apteka, 45 (1116). Available at: http://www.apteka.ua/article/434720
Melzer, J., Saller, R., Schapowal, A., Brignoli, R. (2006). Systematic review of clinical data with BNO–101 (Sinupret) in the treatment of sinusitis. Forsch. Komplementmed, 13 (2), 78–87. doi: 10.1159/000091969
Golusiński, W. (2013). Recommendation for Sinupret as a supplementary specimen in pharmacological treatment of rhinosinusitis. Otolaryngol Pol., 67 (5), 223–227.
Glatthar–Saalmuller, B., Tauchhaus, U., Rode, S. et al. (2011). Antiviral activity of two preparations of the herbal medicinal product Sinupret™ against viruses causing respiratory infections. Phytomedicine, 19 (1), 1–7. doi: 10.1016/j.phymed.2011.10.010
Jund, R., Mondigler, M., Steindl, H. et al. (2012). Clinical efficacy of a dry extract of five herbal drugs in acute viral rhinosinusitis. Rhinology, 50, 417–426.
Lin, W., Quan, C., Zhang, L. (2015). Nasal endoscope negative pressure cleaning and sinupret drops to treat radiation nasosinusitis. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 29 (23), 2019–2022.
Zhangm, S., Skinner, D., Bradley Hicks, S. et al. (2014). Sinupret Activates CFTR and TMEM16A–Dependent Transepithelial Chloride Transport and Improves Indicators of Mucociliary Clearance. PLoSOne, 9 (8). Available at: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104090
Reden, J., El–Hifnawi, D., Zahnert, T., Hummel, T. (2011). The effect of a herbal combination of primrose, gentian root, vervain, elder flowers, and sorrel on olfactory function in patients with a sinonasal olfactory dysfunction. Rhinology, 49 (3), 342–346.
Heather Oliff, S., Blumenthal, M. (2011). Klіnіchna іmunolohіia. Alerholohіia. Іnfektolohiia, 9–10, 48–49.
Kovalenko, V. N., Sur, S. V., Zupanetc, I.A. (2016). Kompendium 2016 – lekarstvennye preparaty. Kiev: Morion, 2320.
Kreindler, J. L., Chen, B., Kreitman, Y. et al. (2012). The novel dry extract BNO 1011 stimulates chloride transport and ciliary beat frequency in human respiratory epithelial cultures. Am J Rhinol Allergy, 26 (6), 439–440. doi: 10.2500/ajra.2012.26.3821
Münch, G. (2012). Experimentelle Untersuchungen zur Wirksamkeit der Pflanzenextrakte des Phytotherapeutikums Sinupret. Christian–Albrechts–Universität, 43.
Seifert, S., Wosikowski, K., Haunschild. J. (2013). Dry extract BNO 1011 inhibits human influenza a replication and neuraminidase activity in oseltamivir–resistant and –sensitive viral strains. Clin Transl Allergy, 3 (2), 20. doi: 10.1186/2045–7022–3–s2–p20
Palm, J., Steiner, I., Abramov–Sommariva, D. et al. (2017). Assessment of efficacy and safety of the herbal medicinal product BNO 1016 inchronic rhinosinusitis. Rhinology, 155 (2), 142–151.
Yund, R., Mondliger, M., Shtammer, Kh. et al. (2016). Vіsnyk № 1. Pryrodna medytsyna, 21 (394), 22–24.
Tykhonov, O. I., Yarnykh, T. H., Zupanets,I.A. et al. (2010). Bіofarmatsіia. Kharkіv : NUPh : Zolotі storinky, 240.
Fokkens, W. J., Lund, V. J., Mullol, J. et al. (2012). EPOS 2012: European position paper on rhinosinusitis and nasal polyps A summary for otorhinolaryngologists. Rhinology, 50 (1), 1–12.
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