Atherosclerosis: therapeutic and preventive possibilities of herbal medicines

Authors

  • I. A. Zupanets National University of Pharmacy, Ukraine
  • A. Tattis National University of Pharmacy, Ukraine
  • S. K. Shebeko National University of Pharmacy, Ukraine
  • I. A. Otrishko National University of Pharmacy, Ukraine
  • A. S. Shalamay PJSC SIC “Borshchahivskiy CPP”, Ukraine
  • O. O. Dobrovolnyi PJSC SIC “Borshchahivskiy CPP”, Ukraine

DOI:

https://doi.org/10.24959/cphj.16.1398

Keywords:

atherosclerosis, prevention, treatment, herbal medicines, Altsinara

Abstract

Diagnosis, treatment and prevention of atherosclerosis remain one of the most important tasks of modern medicine; their solution depends largely on the successful fight against such diseases as heart attack, stroke and other cardiovascular complications. At the present stage of development of medicine the statins are the basic class of lipid-lowering drugs, they have a powerful evidence base and possess the vascular and pleiotropic effects. However, the widespread use of these drugs can sometimes be limited by their high cost and the number of side effects. Therefore, in terms of effective prevention of atherosclerosis lesions herbal medicines are currently of a special interest, in particular those on the basis of garlic powder and artishock extract. The new original drug “Altsinara” developed by PJSC SIC “Borshchahivskiy CPP” is one of them. It has a polytropic mechanism of action and can be used for prevention and treatment of diseases of the cardiovascular, digestive and urinary systems.

References

Беляков К.В. // Consilium medicum. – 2006. – Т. 4, №5. – C. 42.

Клінічна фармакологія : підручник / За ред. О.Я.Бабака, О.М.Біловола, І.С.Чекмана. – 2-ге вид., перероб. і доп. – К. : Медицина, 2010. – 774 с.

Мітченко О.І., Лутай М.І. Дисліпідемії: діагностика, профілактика та лікування: Метод. рекоменд. асоціації кардіологів України. – К.: Четверта хвиля, 2011. – 49 с.

Стрюк Р.И., Травникова Н.Л., Павлова Л.Н. и др. // Практикующий врач. – 2004. – №5. – С. 47-49.

Яцык Г.В., Беляева И.А., Бомбардирова Е.П. // Рос. вестник перинатол. и педиатрии. – 2007. – Т. 52, №2. – С. 20-22.

Blumenthal M. The Complete German Commission E Monographs. Austin, Texas: American Botanical Council, 1998.

Bradley P.R. British Herbal Compendium, Vol. 1. Bournemouth, British Herbal Medicine Association, 1992.

Buddington K.K., Donahoo J.B., Buddington R.K. // J. Nutr. – 2002. – Vol. 132 (3). – P. 472-477.

Bundy R., Walker A.F., Middleton R.W. et al. // Phytomedicine. – 2008. – Vol. 15 (9). – P. 668-675.

European Scientific Co-operative on Phytotherapy. ESCOP monographs. 2nd edition. Exeter, Stuttgart, New York: ESCOP, Georg Thieme Verlag, Thieme New York, 2003.

Ferracane R., Pellegrini N., Visconti A. et al. // J. Agric. Food Chem. – 2008. – Vol. 56 (18). – P. 8601-8608.

Gebhardt R., Beck H., Wagner K.G. // Biocim. Biophys. Acta. – 1994. – Vol. 1213. – P. 57-62.

Harrison’s Principles of Internal Medicine / A.S.Fauci, E.Braunwald, D.L.Kasper et al. – New York : McGraw-Hill Medical, 2008. – 2754 p.

Jimenez E.A., Dragsted L.O., Daneshvar B. et al. // J. Agric. Food Chem. – 2003. – Vol. 51 (18). – P. 5540-5545.

Juzyszyn Z., Czerny B., Pawlik A., Drozdzik M. // Phytother. Res. – 2008. – Vol. 22 (9). – P. 1159-1161.

Kunle O.F., Egharevba H.O., Ahmadu P.O. // Int. J. Biodivers. Conserv. – 2012. – Vol. 4 (3). – P. 101-112.

Lupattelli G., Marchesi S., Lombardini R. et al. // Life Sci. – 2004. – Vol. 76 (7). – P. 775-782.

Mehmetcik G., Ozdemirler G., KocakToker N. et al. // Exp. Toxicol. Pathol. – 2008. – Vol. 60. – P. 475-480. КЛІНІЧНА ФАРМАЦІЯ. – 2016. – Т. 20, № 322 ISSN 1562-725X

Miccadei S., Di Venere D., Cardinali A. et al. // Nutr. Cancer. – 2008. – Vol. 60, №2. – P. 276-283.

Nadova S., Miadokova E., Mucaji P. et al. // Phytother. Res. – 2008. – Vol. 22 (2). – P. 165-168.

New Guide to Medicines & Drugs / J.A.Henry, M.Peters, M.Balic et al. – London: Dorling Kindersley Limited, 2008. – 512 p.

Shimoda H., Ninomiya K., Nishida N. et al. // Bioorg. Med. Chem. Lett. – 2003. – Vol. 13 (2). – P. 223-228.

Tattelman E. // Am. Fam. Physician. – 2005. – Vol. 72. – P. 103-106.

World Health Organization. WHO Monographs on Selected Medicinal Plants, Vol. 1. – Geneva: World Health Organization, 1999.

World Health Organization. WHO Monographs on Selected Medicinal Plants, Vol. 4. – Geneva: World Health Organization, 2009

Downloads

Published

2016-09-02

Issue

Vol. 20 No. 3 (2016)

Section

Clinical Pharmacology and Pharmacotherapy

License

Copyright (c) 2016 National University of Pharmacy

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).